FLOATING A NEW APPROACH FOR GASTRORETENTIVE DRUG DELIVERY SYSTEM: A REVIEW
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چکیده
منابع مشابه
Floating Drug Delivery of Nevirapine as a Gastroretentive System
A multiple-unit floating drug delivery system based on gas formation technique was developed, in order to prolong the gastric residence time and to increase the overall bioavailability of the dosage form. The floating bead formulations were prepared by dispersing nevirapine together with calcium carbonate in a mixture of sodium alginate and hydroxypropyl methylcellulose solution and then drippi...
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Oral delivery of drugs is by far the most preferable route of drug delivery . Oral-rate controlled drug delivery systems have an important area among novel drug delivery system. But these oral sustained release drug delivery systems suffer greatly due to their short gastric residence time/ gastric emptying time. Whereas prolonged gastric residence increases duration of drug release, reduces dru...
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Oral administration of dosage form is the priority for the patients as per its easy administration, economical formulation and various other reasons. Drugs having good absorption in proximal gastrointestinal tract (GIT) part possess bioavailability problem due to less gastric residence time of drug in the stomach. Thus superporous hydrogel (SPH) is a supreme approach to deliver the drug in uppe...
متن کاملFloating Drug Delivery System: a Review
The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the types of floating drug delivery systems, principal and mechanism of floatation to achieve gastric retention. Drug delivery systems are those that float immediately upon contact with gastric fluids present promising approaches for increasing the bioavailabili...
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Management of infirmity through medication is entering a new era in which growing number of novel drug delivery systems are being employed and are available for therapeutic use. Oral sustained release gastro-retentive dosage forms (GRDFs) offer many advantages for drugs with absorption from upper parts of gastrointestinal tract and for those acting locally in the stomach, improving the bioavail...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Education and Research
سال: 2020
ISSN: 2278-7496
DOI: 10.38164/ajper/9.2.2020.1-14